Sr were originally identified by their ability to bind and internalize modified lipoproteins and microorganisms but also particles and tlr agonists. Handbook of dendritic cells biology, diseases and therapy. Immature dendritic cells dc represent potential clinical tools for tolerogenic cellular immunotherapy in both transplantation and autoimmunity. They traffic from the blood to the tissues where, while immature, they capture antigens.
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To do so they need to mature and migrate to sites of t-cell priming. The most efficient antigen-presenting cells apcs are mature, immunologically competent dendritic cells dcs. A sexy big tit woman topless at the beach.
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During inflammation, murine and human monocytes can develop into dendritic cells dc, but this process is not entirely understood.
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